A novel P-QRS-T wave localization method in ECG signals based on hybrid neural networks.

Journal: Computers in biology and medicine
Published Date:

Abstract

As the number of people suffering from cardiovascular diseases increases every year, it becomes essential to have an accurate automatic electrocardiogram (ECG) diagnosis system. Researchers have adopted different methods, such as deep learning, to investigate arrhythmias classification. However, the importance of ECG waveform features is generally ignored when deep learning approaches are applied to classification tasks. P-wave, QRS-wave, and T-wave, containing plenty of physiological information, are three critical waves in the ECG heartbeat. The accurate localization of these critical ECG wave components is a prerequisite for ECG classification and diagnosis. In this study, a novel P-QRS-T wave localization method based on hybrid neural networks is proposed. The raw ECG signal is preprocessed sequentially by filtering, heartbeat extraction, and data standardization. The hybrid neural network is constructed by combining the residual neural network (ResNet) and the Long Short-Term Memory (LSTM). It predicts the relative positions of the P-peak, QRS-peak, and T-peak for each heartbeat. The proposed algorithm was validated on four ECG databases with input noise of different signal-to-noise ratio (SNR) levels. The results show that the proposed method can accurately predict the positions of the three key waves. The proposed P-QRS-T localization approach can improve the efficiency of ECG delineation. Integrated with cardiac disease classification methods, it can contribute to the development of advanced automatic ECG diagnosis systems.

Authors

  • Jinlei Liu
    School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Yanrui Jin
    School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Yunqing Liu
    School of Mechanical Engineering, Shanghai Jiao Tong University, Shanghai, China.
  • Zhiyuan Li
    School of Clinical Medicine, General Hospital of Ningxia Medical University, Yinchuan, China.
  • Chengjin Qin
    School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China.
  • Xiaojun Chen
    Department of Gynecology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
  • Liqun Zhao
    Department of Cardiology, Shanghai First People's Hospital Affiliated to Shanghai Jiao Tong University, 100, Haining Road, Shanghai 200080, PR China.
  • Chengliang Liu
    School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai 200240, PR China. Electronic address: chlliu@sjtu.edu.cn.