Human blastocyst spontaneous collapse is associated with worse morphological quality and higher degeneration and aneuploidy rates: a comprehensive analysis standardized through artificial intelligence.

Journal: Human reproduction (Oxford, England)
PMID:

Abstract

STUDY QUESTION: What are the factors associated with human blastocyst spontaneous collapse and the consequences of this event?

Authors

  • Danilo Cimadomo
    GeneraLife IVF, Clinica Valle Giulia, Rome, Italy. Electronic address: cimadomo@generaroma.it.
  • Anabella Marconetto
    University Institute of Reproductive Medicine, National University of Córdoba, Córdoba, Argentina.
  • Samuele Trio
    Clinica Valle Giulia, GeneraLife IVF, Rome, Italy.
  • Viviana Chiappetta
    Clinica Valle Giulia, GeneraLife IVF, Rome, Italy.
  • Federica Innocenti
    Clinica Valle Giulia, GeneraLife IVF, Rome, Italy.
  • Laura Albricci
    Clinica Valle Giulia, GeneraLife IVF, Rome, Italy.
  • Itay Erlich
    The Alexander Grass Center for Bioengineering, School of Computer Science and Engineering, Hebrew University of Jerusalem, Jerusalem, Israel.
  • Assaf Ben-Meir
    Fertility and IVF Unit, Department of Obstetrics and Gynecology, The Hebrew University Hadassah Medical Center, Jerusalem, Israel.
  • Iris Har-Vardi
    Fairtilty Ltd, Tel Aviv, Israel.
  • Ben Kantor
    Fairtilty Ltd, Tel Aviv, Israel.
  • Anat Sakov
    DataSights Ltd, Tel Aviv, Israel.
  • Giovanni Coticchio
    9.baby Family and Fertility Center, Via Dante, 15, Bologna 40125, Italy. Electronic address: giovanni.coticchio@nove.baby.
  • Andrea Borini
    9.baby Family and Fertility Center, Via Dante, 15, Bologna 40125, Italy.
  • Filippo Maria Ubaldi
    Clinica Valle Giulia, GeneraLife IVF, Rome, Italy.
  • Laura Rienzi
    GeneraLife IVF, Clinica Valle Giulia, Rome, Italy.