Automation of generative adversarial network-based synthetic data-augmentation for maximizing the diagnostic performance with paranasal imaging.

Journal: Scientific reports
Published Date:

Abstract

Thus far, there have been no reported specific rules for systematically determining the appropriate augmented sample size to optimize model performance when conducting data augmentation. In this paper, we report on the feasibility of synthetic data augmentation using generative adversarial networks (GAN) by proposing an automation pipeline to find the optimal multiple of data augmentation to achieve the best deep learning-based diagnostic performance in a limited dataset. We used Waters' view radiographs for patients diagnosed with chronic sinusitis to demonstrate the method developed herein. We demonstrate that our approach produces significantly better diagnostic performance parameters than models trained using conventional data augmentation. The deep learning method proposed in this study could be implemented to assist radiologists in improving their diagnosis. Researchers and industry workers could overcome the lack of training data by employing our proposed automation pipeline approach in GAN-based synthetic data augmentation. This is anticipated to provide new means to overcome the shortage of graphic data for algorithm training.

Authors

  • Hyoun-Joong Kong
    Department of Biomedical Engineering, Chungnam National University College of Medicine, Daejeon, Korea.
  • Jin Youp Kim
    Department of Otorhinolaryngology-Head and Neck Surgery, Ilsan Hospital, Dongguk University, Goyang, Gyeonggi, Korea.
  • Hye-Min Moon
    Interdisciplinary for Bioengineering, Seoul National University, Jongno-Gu, Seoul, 03080, Republic of Korea.
  • Hae Chan Park
    Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Gyeonggi, 13620, Republic of Korea.
  • Jeong-Whun Kim
    Department of Otorhinolaryngology, Seoul National University Bundang Hospital, 82, Gumi-ro, Bundang-gu, Seongnam, Republic of Korea.
  • Ruth Lim
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
  • Jonghye Woo
    Gordon Center for Medical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.
  • Georges El Fakhri
    Gordon Center of Medical Imaging, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Dae Woo Kim
    Department of Otorhinolaryngology-Head and Neck Surgery, Boramae Medical Center, Seoul Metropolitan Government-Seoul National University 20, Boramae-Ro 5-Gil, Dongjak-Gu, Seoul, 07061, Republic of Korea. kicubi@hanmail.net.
  • Sungwan Kim
    Department of Biomedical Engineering, Seoul National University College of Medicine, Seoul, Republic of Korea.