Multi-objective data enhancement for deep learning-based ultrasound analysis.

Journal: BMC bioinformatics
Published Date:

Abstract

Recently, Deep Learning based automatic generation of treatment recommendation has been attracting much attention. However, medical datasets are usually small, which may lead to over-fitting and inferior performances of deep learning models. In this paper, we propose multi-objective data enhancement method to indirectly scale up the medical data to avoid over-fitting and generate high quantity treatment recommendations. Specifically, we define a main and several auxiliary tasks on the same dataset and train a specific model for each of these tasks to learn different aspects of knowledge in limited data scale. Meanwhile, a Soft Parameter Sharing method is exploited to share learned knowledge among models. By sharing the knowledge learned by auxiliary tasks to the main task, the proposed method can take different semantic distributions into account during the training process of the main task. We collected an ultrasound dataset of thyroid nodules that contains Findings, Impressions and Treatment Recommendations labeled by professional doctors. We conducted various experiments on the dataset to validate the proposed method and justified its better performance than existing methods.

Authors

  • Chengkai Piao
    College of Computer Science, Nankai University, Tianjin, China.
  • Mengyue Lv
    Department of Ultrasound, Cangzhou Municipal Haixing Hospital, Cangzhou, China.
  • Shujie Wang
    Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, China.
  • Rongyan Zhou
    Department of Ultrasound, Cangzhou Municipal Haixing Hospital, Cangzhou, China.
  • Yuchen Wang
    College of Management, University of Massachusetts Boston, Boston, MA, USA.
  • Jinmao Wei
    College of Computer Science, Nankai University, Tianjin, China. weijm@nankai.edu.cn.
  • Jian Liu
    Department of Rheumatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China.