Transfusion-associated hyperkalemia in pediatric population: Analyses for risk factors and recommendations.

Journal: Transfusion
Published Date: Oct 4, 2022

Abstract

BACKGROUND: Transfusion-associated hyperkalemia (TAH) is a potentially life-threatening complication of red blood cell (RBC) transfusion. Previously, we reported features of RBC transfusions from 35 pediatric patients (TAH group) who had hyperkalemia with RBC transfusion in one-year period at four facilities. In this study, we used multivariate analyses and artificial intelligence to compare the TAH group to newly collected control group (non-TAH group) to identify factors associated with TAH occurrence.

Authors

  • Chisa Yamada
    Department of Pathology, Division of Transfusion Medicine, University of Michigan, Ann Arbor, Michigan, USA.
  • Maureen F Edelson
    Blood Bank and Stem Cell Processing Laboratory, Nemours Children's Hospital, Wilmington, Delaware, USA.
  • Angela C Lee
    Division of Anesthesiology, Pain and Perioperative Medicine, Children's National Hospital, George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
  • Nabiha H Saifee
    Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, Seattle Children's and University of Washington, Seattle, Washington, USA.
  • Ivo D Dinov
    Laboratory of Neuro Imaging, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA; Statistics Online Computational Resource, Department of Health Behavior and Biological, University of Michigan, Ann Arbor, MI, USA.

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