Assessing the Severity of COVID-19 Lung Injury in Rheumatic Diseases Versus the General Population Using Deep Learning-Derived Chest Radiograph Scores.

Journal: Arthritis care & research
PMID:

Abstract

OBJECTIVE: COVID-19 patients with rheumatic disease have a higher risk of mechanical ventilation than the general population. The present study was undertaken to assess lung involvement using a validated deep learning algorithm that extracts a quantitative measure of radiographic lung disease severity.

Authors

  • Naomi J Patel
    Massachusetts General Hospital and Harvard Medical School, Boston.
  • Kristin M D'Silva
    Massachusetts General Hospital and Harvard Medical School, Boston.
  • Matthew D Li
    Department of Radiology, Harvard Medical School/Massachusetts General Hospital, Boston, Massachusets.
  • Tiffany Y T Hsu
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Michael DiIorio
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Xiaoqing Fu
    Massachusetts General Hospital and Harvard Medical School, Boston.
  • Claire Cook
    Massachusetts General Hospital and Harvard Medical School, Boston.
  • Lauren Prisco
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Lily Martin
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Kathleen M M Vanni
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Alessandra Zaccardelli
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Yuqing Zhang
    Division of Rheumatology, Allergy, and Immunology, Harvard Medical School, 2348Massachusetts General Hospital, Boston, MA, USA.
  • Jayashree Kalpathy-Cramer
    Department of Radiology, MGH/Harvard Medical School, Charlestown, Massachusetts.
  • Jeffrey A Sparks
    Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Zachary S Wallace
    Massachusetts General Hospital and Harvard Medical School, Boston.