Brain-Computer Interface-Controlled Exoskeletons in Clinical Neurorehabilitation: Ready or Not?

Journal: Neurorehabilitation and neural repair
Published Date:

Abstract

The development of brain-computer interface-controlled exoskeletons promises new treatment strategies for neurorehabilitation after stroke or spinal cord injury. By converting brain/neural activity into control signals of wearable actuators, brain/neural exoskeletons (B/NEs) enable the execution of movements despite impaired motor function. Beyond the use as assistive devices, it was shown that-upon repeated use over several weeks-B/NEs can trigger motor recovery, even in chronic paralysis. Recent development of lightweight robotic actuators, comfortable and portable real-world brain recordings, as well as reliable brain/neural control strategies have paved the way for B/NEs to enter clinical care. Although B/NEs are now technically ready for broader clinical use, their promotion will critically depend on early adopters, for example, research-oriented physiotherapists or clinicians who are open for innovation. Data collected by early adopters will further elucidate the underlying mechanisms of B/NE-triggered motor recovery and play a key role in increasing efficacy of personalized treatment strategies. Moreover, early adopters will provide indispensable feedback to the manufacturers necessary to further improve robustness, applicability, and adoption of B/NEs into existing therapy plans.

Authors

  • Annalisa Colucci
    Clinical Neurotechnology Laboratory, Neurowissenschaftliches Forschungszentrum (NWFZ), Department of Psychiatry and Neurosciences, Charité Campus Mitte (CCM), Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
  • Mareike Vermehren
    Clinical Neurotechnology Laboratory, Neurowissenschaftliches Forschungszentrum (NWFZ), Department of Psychiatry and Neurosciences, Charité Campus Mitte (CCM), Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
  • Alessia Cavallo
    Clinical Neurotechnology Laboratory, Neurowissenschaftliches Forschungszentrum (NWFZ), Department of Psychiatry and Neurosciences, Charité Campus Mitte (CCM), Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
  • Cornelius Angerhöfer
    Clinical Neurotechnology Laboratory, Neurowissenschaftliches Forschungszentrum (NWFZ), Department of Psychiatry and Neurosciences, Charité Campus Mitte (CCM), Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
  • Niels Peekhaus
    Clinical Neurotechnology Laboratory, Neurowissenschaftliches Forschungszentrum (NWFZ), Department of Psychiatry and Neurosciences, Charité Campus Mitte (CCM), Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.
  • Loredana Zollo
  • Won-Seok Kim
    Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital.
  • Nam-Jong Paik
    Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital; njpaik@snu.ac.kr.
  • Surjo R Soekadar