Clinical feasibility of deep learning-based automatic head CBCT image segmentation and landmark detection in computer-aided surgical simulation for orthognathic surgery.

Journal: International journal of oral and maxillofacial surgery
PMID:

Abstract

The purpose of this ambispective study was to investigate whether deep learning-based automatic segmentation and landmark detection, the SkullEngine, could be used for orthognathic surgical planning. Sixty-one sets of cone beam computed tomography (CBCT) images were automatically inferred for midface, mandible, upper and lower teeth, and 68 landmarks. The experimental group included automatic segmentation and landmarks, while the control group included manual ones that were previously used to plan orthognathic surgery. The qualitative analysis of segmentation showed that all of the automatic results could be used for computer-aided surgical simulation. Among these, 98.4% of midface, 70.5% of mandible, 98.4% of upper teeth, and 93.4% of lower teeth could be directly used without manual revision. The Dice similarity coefficient was 96% and the average symmetric surface distance was 0.1 mm for all four structures. With SkullEngine, it took 4 minutes to complete the automatic segmentation and an additional 10 minutes for a manual touchup. The results also showed the overall mean difference between the two groups was 2.3 mm for the midface and 2.4 mm for the mandible. In summary, the authors believe that automatic segmentation using SkullEngine is ready for daily practice. However, the accuracy of automatic landmark digitization needs to be improved.

Authors

  • H H Deng
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA. Electronic address: hdeng@HoustonMethodist.org.
  • Q Liu
    Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
  • A Chen
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • T Kuang
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • P Yuan
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • J Gateno
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA; Department of Surgery (Oral and Maxillofacial Surgery), Weill Medical College, Cornell University, New York, New York, USA.
  • D Kim
    Department of Pharmaceutical Sciences, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center , College Station, Texas 77843, United States.
  • J C Barber
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • K G Xiong
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • P Yu
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • K J Gu
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA.
  • X Xu
    From the Department of Radiology (W.H., C.B., X.C., N.M., A.L., X.X., G.Y.), Brigham and Women's Hospital, Boston, Massachusetts.
  • P Yan
    Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.
  • D Shen
    University of North Carolina, Department of Radiology and BRIC, Chapel Hill, NC, USA.
  • J J Xia
    Department of Oral and Maxillofacial Surgery, Houston Methodist Research Institute, Houston, Texas, USA; Department of Surgery (Oral and Maxillofacial Surgery), Weill Medical College, Cornell University, New York, New York, USA. Electronic address: jamesjxiamdphd@gmail.com.