Learning temporal difference embeddings for biomedical hypothesis generation.

Journal: Bioinformatics (Oxford, England)
Published Date:

Abstract

MOTIVATION: Hypothesis generation (HG) refers to the discovery of meaningful implicit connections between disjoint scientific terms, which is of great significance for drug discovery, prediction of drug side effects and precision treatment. More recently, a few initial studies attempt to model the dynamic meaning of the terms or term pairs for HG. However, most existing methods still fail to accurately capture and utilize the dynamic evolution of scientific term relations.

Authors

  • Huiwei Zhou
    School of Computer Science and Technology, Dalian University of Technology, Dalian, Liaoning, China.
  • Haibin Jiang
    College of Computer Science and Technology, Dalian University of Technology, Dalian, Liaoning 116024, China.
  • Weihong Yao
    School of Computer Science and Technology, Dalian University of Technology, Dalian 116024, Liaoning, China. Electronic address: weihongy@dlut.edu.cn.
  • Xun Du
    College of Computer Science and Technology, Dalian University of Technology, Dalian, Liaoning 116024, China.