The monitoring of oil production process by deep learning based on morphology in oleaginous yeasts.

Journal: Applied microbiology and biotechnology
PMID: 36576569

Abstract

BACKGROUND: Monitoring jar fermenter-cultured microorganisms in real time is important for controlling productivity of bioproducts in large-scale cultivation settings. Morphological data is used to understand the growth and fermentation states of these microorganisms during monitoring. Oleaginous yeasts are used for their high productivity of single-cell oils but the relationship between lipid productivity and morphology has not been elucidated in these organisms.

Authors

  • Yukina Kitahara
    Department of Science of Technology Innovation, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Ayaka Itani
    Department of Bioengineering, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Kazuma Ohtomo
    Department of Information Science and Control Engineering, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Yosuke Oda
    Department of Mechanical Engineering, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Yuka Takahashi
    Department of Gastroenterology and Hepatology Musashino Red Cross Hospital Tokyo Japan.
  • Makoto Okamura
    NRI System Techno Ltd, 4-4-1 Minato Mirai, Nishi-Ku, Yokohama, 220-0012, Japan.
  • Mizue Mizoshiri
    Department of Mechanical Engineering, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Yosuke Shida
    Department of Bioengineering, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Toru Nakamura
  • Ryosuke Harakawa
    Department of Electrical Electronics and Information Engineering, Nagaoka University of Technology, 1603-1, Kamitomioka, Nagaoka, Niigata, 940-2188, Japan.
  • Masahiro Iwahashi
  • Wataru Ogasawara
    Department of Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata, Japan.

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