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Yeasts

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The Genome3D Consortium for Structural Annotations of Selected Model Organisms.

Methods in molecular biology (Clifton, N.J.)
Genome3D consortium is a collaborative project involving protein structure prediction and annotation resources developed by six world-leading structural bioinformatics groups, based in the United Kingdom (namely Blundell, Murzin, Gough, Sternberg, Or...

A fully automated deep learning pipeline for high-throughput colony segmentation and classification.

Biology open
Adenine auxotrophy is a commonly used non-selective genetic marker in yeast research. It allows investigators to easily visualize and quantify various genetic and epigenetic events by simply reading out colony color. However, manual counting of large...

Complementary performances of convolutional and capsule neural networks on classifying microfluidic images of dividing yeast cells.

PloS one
Microfluidic-based assays have become effective high-throughput approaches to examining replicative aging of budding yeast cells. Deep learning may offer an efficient way to analyze a large number of images collected from microfluidic experiments. He...

Computational identification of ubiquitination sites in Arabidopsis thaliana using convolutional neural networks.

Plant molecular biology
We developed two CNNs for predicting ubiquitination sites in Arabidopsis thaliana, demonstrated their competitive performance, analyzed amino acid physicochemical properties and the CNN structures, and predicted ubiquitination sites in Arabidopsis. A...

Convolutional neural network analysis of recurrence plots for high resolution melting classification.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: High resolution melting (HRM) analysis is a rapid and correct method for identification of species, such as, microorganism, bacteria, yeast, virus, etc. HRM data are produced using real-time polymerase chain reaction (PCR) a...

Prediction and collection of protein-metabolite interactions.

Briefings in bioinformatics
Interactions between proteins and small molecule metabolites play vital roles in regulating protein functions and controlling various cellular processes. The activities of metabolic enzymes, transcription factors, transporters and membrane receptors ...

A Novel Feature Selection Method for Uncertain Features: An Application to the Prediction of Pro-/Anti-Longevity Genes.

IEEE/ACM transactions on computational biology and bioinformatics
Understanding the ageing process is a very challenging problem for biologists. To help in this task, there has been a growing use of classification methods (from machine learning) to learn models that predict whether a gene influences the process of ...

The monitoring of oil production process by deep learning based on morphology in oleaginous yeasts.

Applied microbiology and biotechnology
BACKGROUND: Monitoring jar fermenter-cultured microorganisms in real time is important for controlling productivity of bioproducts in large-scale cultivation settings. Morphological data is used to understand the growth and fermentation states of the...

Automated quantification of lipid contents of Lipomyces starkeyi using deep-learning-based image segmentation.

Bioresource technology
Intracellular lipid droplets (LDs), subcellular organelles playing a role in long-term carbon storage, have immense potential in biofuel and dietary lipid production. Monitoring the state of LDs in living cells is of utmost importance for quick bioma...

Deep learning enabled rapid classification of yeast species in food by imaging of yeast microcolonies.

Food research international (Ottawa, Ont.)
Diverse species of yeasts are commonly associated with food and food production environments. The contamination of food products by spoilage yeasts poses significant challenges, leading to quality degradation and food loss. Similarly, the introductio...