Accuracy and efficiency of an artificial intelligence-based pulmonary broncho-vascular three-dimensional reconstruction system supporting thoracic surgery: retrospective and prospective validation study.

Journal: EBioMedicine
Published Date:

Abstract

BACKGROUND: Anthropomorphic phantoms are used in surgical planning and intervention. Ideal accuracy and high efficiency are prerequisites for its clinical application. We aimed to develop a fully automated artificial intelligence-based three-dimensional (3D) reconstruction system (AI system) to assist thoracic surgery and to determine its accuracy, efficiency, and safety for clinical use.

Authors

  • Xiang Li
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
  • Shanyuan Zhang
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China.
  • Xiang Luo
    Linkdoc AI Research (LAIR), Linkdoc Information Technology (Beijing) Co., Ltd., Beijing, China.
  • Guangming Gao
    LinkDoc Technology, Beijing, China.
  • Xiangfeng Luo
    LinkDoc Technology, Beijing, China.
  • Shansi Wang
    Linkdoc AI Research (LAIR), Linkdoc Information Technology (Beijing) Co., Ltd., Beijing, China.
  • Shaolei Li
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China.
  • Dachuan Zhao
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China.
  • Yaqi Wang
    Key Laboratory of RF Circuits and Systems, Ministry of Education, Hangzhou Dianzi University, Hangzhou 310018, China.
  • Xinrun Cui
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China.
  • Bing Liu
    Department of Cardiovascular Surgery, the Sixth Medical Centre of Chinese PLA General Hospital, 100048 Beijing, China.
  • Ye Tao
    Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
  • Bufan Xiao
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China.
  • Lei Tang
    Department of Neurology, Xiangya Hospital, Central South University, Jiangxi, Nanchang, 330006, Jiangxi, China.
  • Shi Yan
    Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing, China.
  • Nan Wu
    Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, National Center of Excellence for Computational Drug Abuse Research, Drug Discovery Institute, Departments of Computational Biology and Structural Biology, School of Medicine , University of Pittsburgh , Pittsburgh , Pennsylvania 15261 , United States.