Diffusion-weighted MRI with deep learning for visualizing treatment results of MR-guided HIFU ablation of uterine fibroids.

Journal: European radiology
Published Date: Jun 1, 2023

Abstract

OBJECTIVES: No method is available to determine the non-perfused volume (NPV) repeatedly during magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) ablations of uterine fibroids, as repeated acquisition of contrast-enhanced T1-weighted (CE-T1w) scans is inhibited by safety concerns. The objective of this study was to develop and test a deep learning-based method for translation of diffusion-weighted imaging (DWI) into synthetic CE-T1w scans, for monitoring MR-HIFU treatment progression.

Authors

  • Derk J Slotman
    Department of Radiology, Isala Hospital, Zwolle, The Netherlands. d.j.slotman@isala.nl.
  • Lambertus W Bartels
    Imaging & Oncology Division, Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Aylene Zijlstra
    Department of Radiology, Isala Hospital, Zwolle, The Netherlands.
  • Inez M Verpalen
    Department of Radiology, Isala Hospital, Zwolle, The Netherlands.
  • Jochen A C van Osch
    Department of Medical Physics, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands.
  • Ingrid M Nijholt
    Department of Radiology and Nuclear Medicine, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands.
  • Edwin Heijman
    Faculty of Medicine and University Hospital of Cologne, Institute of Diagnostic and Interventional Radiology, University of Cologne, Cologne, Germany.
  • Miranda van 't Veer-Ten Kate
    Department of Radiology, Isala Hospital, Zwolle, The Netherlands.
  • Erwin de Boer
    Department of Radiology, Isala Hospital, Zwolle, The Netherlands.
  • Rolf D van den Hoed
    Department of Radiology, Isala Hospital, Zwolle, The Netherlands.
  • Martijn Froeling
    Department of Radiology, University Medical Center Utrecht, Utrecht, the Netherlands.
  • Martijn F Boomsma
    Department of Radiology and Nuclear Medicine, Isala, P.O. Box 10400, 8000 GK Zwolle, The Netherlands.

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