Neuron tracing from light microscopy images: automation, deep learning and bench testing.

Journal: Bioinformatics (Oxford, England)
Published Date: Dec 13, 2022

Abstract

MOTIVATION: Large-scale neuronal morphologies are essential to neuronal typing, connectivity characterization and brain modeling. It is widely accepted that automation is critical to the production of neuronal morphology. Despite previous survey papers about neuron tracing from light microscopy data in the last decade, thanks to the rapid development of the field, there is a need to update recent progress in a review focusing on new methods and remarkable applications.

Authors

  • Yufeng Liu
    Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC.
  • Gaoyu Wang
    School of Computer Science and Engineering, Southeast University, Nanjing, China.
  • Giorgio A Ascoli
    Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA. Electronic address: ascoli@gmu.edu.
  • Jiangning Zhou
    Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, China.
  • Lijuan Liu
    New Cornerstone Science Laboratory, SEU-ALLEN Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, Jiangsu 210096, China.

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