Development and Validation of a Deep Learning Algorithm to Differentiate Colon Carcinoma From Acute Diverticulitis in Computed Tomography Images.

Journal: JAMA network open
Published Date:

Abstract

IMPORTANCE: Differentiating between malignant and benign etiology in large-bowel wall thickening on computed tomography (CT) images can be a challenging task. Artificial intelligence (AI) support systems can improve the diagnostic accuracy of radiologists, as shown for a variety of imaging tasks. Improvements in diagnostic performance, in particular the reduction of false-negative findings, may be useful in patient care.

Authors

  • Sebastian Ziegelmayer
    Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Stefan Reischl
    Institute of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine, Munich, Germany.
  • Hannah Havrda
    Institute of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine, Munich, Germany.
  • Joshua Gawlitza
    Department for Cardiothoracic Imaging, Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Homburg, Germany.
  • Markus Gräf
    Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Nicolas Lenhart
    Institute of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine, Munich, Germany.
  • Nadja Nehls
    Institute of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine, Munich, Germany.
  • Tristan Lemke
    Institute of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine, Munich, Germany.
  • Dirk Wilhelm
    Department of Surgery, Research Group Minimally Invasive Interdisciplinary Therapeutical Intervention (MITI), Klinikum rechts der Isar, Technical University Munich (TUM), Munich, Germany, Department of Surgery, Klinikum rechts der Isar, Technical University Munich (TUM), Munich, Germany.
  • Fabian Lohöfer
    Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Egon Burian
    Institute of Diagnostic and Interventional Radiology, Technical University of Munich, School of Medicine, Munich, Germany.
  • Philipp-Alexander Neumann
    Department of Surgery, Technical University of Munich, School of Medicine, Munich, Germany.
  • Marcus Makowski
    German Cancer Consortium, Heidelberg, Germany.
  • Rickmer Braren
    Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany.