Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes.

Journal: NeuroImage. Clinical
Published Date:

Abstract

OBJECTIVE: To diagnose and lateralise temporal lobe epilepsy (TLE) by building a classification system that uses directed functional connectivity patterns estimated during EEG periods without visible pathological activity.

Authors

  • Thibault Verhoeven
    Department of Electronics and Information Systems, Ghent University, Ghent, Belgium. Electronic address: thibault.verhoeven@ugent.be.
  • Ana Coito
    Functional Brain Mapping Lab, Department of Basic Neuroscience, University of Geneva, Geneva, Switzerland.
  • Gijs Plomp
    Perceptual Networks Group, Department of Psychology, University of Fribourg, Fribourg, Switzerland.
  • Aljoscha Thomschewski
    Department of Neurology, Paracelsus Medical University and Center for Cognitive Neuroscience, Salzburg, Austria.
  • Francesca Pittau
    Epilepsy Unit, Neurology Clinic, University Hospital of Geneva, Geneva, Switzerland.
  • Eugen Trinka
    Department of Neurology, Paracelsus Medical University and Center for Cognitive Neuroscience, Salzburg, Austria.
  • Roland Wiest
    Institute for Diagnostic and Interventional Neuroradiology, University of Bern, Bern, Switzerland.
  • Karl Schaller
    Neurosurgery Clinic, University Hospital Geneva, Geneva, Switzerland.
  • Christoph Michel
    Functional Brain Mapping Lab, Department of Basic Neuroscience, University of Geneva, Geneva, Switzerland.
  • Margitta Seeck
    Epilepsy Unit, Neurology Clinic, University Hospital of Geneva, Geneva, Switzerland.
  • Joni Dambre
    Department of Electronics and Information Systems, Ghent University, Ghent, Belgium.
  • Serge Vulliemoz
    Epilepsy Unit, Neurology Clinic, University Hospital of Geneva, Geneva, Switzerland.
  • Pieter van Mierlo
    Department of Electronics and Information Systems, Ghent University, Ghent, Belgium; Functional Brain Mapping Lab, Department of Basic Neuroscience, University of Geneva, Geneva, Switzerland.