This work aims to promote early and accurate diagnosis of Temporal Lobe Epilepsy (TLE) by developing state-of-the-art deep learning techniques, with the goal of minimizing the consequences of epilepsy on individuals and society. Current approaches fo...
International journal of psychophysiology : official journal of the International Organization of Psychophysiology
Apr 28, 2025
OBJECTIVE: Temporale lobe and occipito-temporal cortical areas play an important role in facial emotion perception (FEP). FEP might be represented by event-related brain oscillations. In patients with temporal lobe epilepsy (TLE), impairment of FEP w...
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
Mar 13, 2025
INTRODUCTION: Localizing the epileptogenic zone (EZ) using Stereo EEG (SEEG) is often challenging through manual analysis. Even methods based on signal analysis have limitations in identifying the EZ, particularly in patients with neocortical epileps...
Approximately 30%-40% of epilepsy patients do not respond well to adequate anti-seizure medications (ASMs), a condition known as pharmacoresistant epilepsy. The management of pharmacoresistant epilepsy remains an intractable issue in the clinic. Its ...
Neural networks : the official journal of the International Neural Network Society
Nov 28, 2024
In neuroscience, phase synchronization (PS) is a crucial mechanism that facilitates information processing and transmission between different brain regions. Specifically, global phase synchronization (GPS) characterizes the degree of PS among multiva...
BACKGROUND: Mesial temporal sclerosis (MTS) is the most common pathology associated with drug-resistant mesial temporal lobe epilepsy (mTLE) in adults. Most atrophic hippocampi can be identified using MRI based on standard epilepsy protocols; however...
Brain resection is curative for a subset of patients with drug resistant epilepsy but up to half will fail to achieve sustained seizure freedom in the long term. There is a critical need for accurate prediction tools to identify patients likely to ha...
Temporal lobe epilepsy (TLE) stands as the predominant adult focal epilepsy syndrome, characterized by dysfunctional intrinsic brain dynamics. However, the precise mechanisms underlying seizures in these patients remain elusive. Our study encompassed...
OBJECTIVE: Individuals with temporal lobe epilepsy (TLE) frequently demonstrate impairments in executive function, working memory, and/or declarative memory. It is recommended that screening for cognitive impairment is undertaken in all people newly ...
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