OBJECTIVE: Normal interictal [ F]FDG-PET can be predicted from the corresponding T1w MRI with Generative Adversarial Networks (GANs). A technique we call SIPCOM (Subtraction Interictal PET Co-registered to MRI) can then be used to compare epilepsy pa...
OBJECTIVE: Individuals with temporal lobe epilepsy (TLE) frequently demonstrate impairments in executive function, working memory, and/or declarative memory. It is recommended that screening for cognitive impairment is undertaken in all people newly ...
OBJECTIVE: To evaluate the diagnostic performance and image quality of 1.5-mm slice thickness MRI with deep learning-based image reconstruction (1.5-mm MRI + DLR) compared to routine 3-mm slice thickness MRI (routine MRI) and 1.5-mm slice thickness M...
Temporal lobe epilepsy (TLE) stands as the predominant adult focal epilepsy syndrome, characterized by dysfunctional intrinsic brain dynamics. However, the precise mechanisms underlying seizures in these patients remain elusive. Our study encompassed...
Brain resection is curative for a subset of patients with drug resistant epilepsy but up to half will fail to achieve sustained seizure freedom in the long term. There is a critical need for accurate prediction tools to identify patients likely to ha...
Neural networks : the official journal of the International Neural Network Society
39626530
In neuroscience, phase synchronization (PS) is a crucial mechanism that facilitates information processing and transmission between different brain regions. Specifically, global phase synchronization (GPS) characterizes the degree of PS among multiva...
Approximately 30%-40% of epilepsy patients do not respond well to adequate anti-seizure medications (ASMs), a condition known as pharmacoresistant epilepsy. The management of pharmacoresistant epilepsy remains an intractable issue in the clinic. Its ...
BACKGROUND: Mesial temporal sclerosis (MTS) is the most common pathology associated with drug-resistant mesial temporal lobe epilepsy (mTLE) in adults. Most atrophic hippocampi can be identified using MRI based on standard epilepsy protocols; however...
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
40086096
INTRODUCTION: Localizing the epileptogenic zone (EZ) using Stereo EEG (SEEG) is often challenging through manual analysis. Even methods based on signal analysis have limitations in identifying the EZ, particularly in patients with neocortical epileps...