Transformer guided progressive fusion network for 3D pancreas and pancreatic mass segmentation.

Journal: Medical image analysis
Published Date:

Abstract

Pancreatic masses are diverse in type, often making their clinical management challenging. This study aims to address the task of various types of pancreatic mass segmentation and detection while accurately segmenting the pancreas. Although convolution operation performs well at extracting local details, it experiences difficulty capturing global representations. To alleviate this limitation, we propose a transformer guided progressive fusion network (TGPFN) that utilizes the global representation captured by the transformer to supplement long-range dependencies lost by convolution operations at different resolutions. TGPFN is built on a branch-integrated network structure, where the convolutional neural network and transformer branches first perform separate feature extraction in the encoder, and then the local and global features are progressively fused in the decoder. To effectively integrate the information of the two branches, we design a transformer guidance flow to ensure feature consistency, and present a cross-network attention module to capture the channel dependencies. Extensive experiments with nnUNet (3D) show that TGPFN improves the mass segmentation (Dice: 73.93% vs. 69.40%) and detection accuracy (detection rate: 91.71% vs. 84.97%) on 416 private CTs, and also obtains performance improvements of mass segmentation (Dice: 43.86% vs. 42.07%) and detection (detection rate: 83.33% vs. 71.74%) on 419 public CTs.

Authors

  • Taiping Qu
    Deepwise AI Lab, Deepwise Inc., Beijing, China.
  • Xiuli Li
    Department of Obstetrics and Gynecology, General Hospital of Chinese People's Liberation Army, Beijing 100853, China.
  • Xiheng Wang
    Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Shuaifuyuan No.1, Wangfujing Street, Dongcheng District, Beijing, 100730, People's Republic of China.
  • Wenyi Deng
    Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.
  • Li Mao
    Deepwise AI Lab, Deepwise Inc, No.8 Haidian avenue, Sinosteel International Plaza, Beijing, 100080, China.
  • Ming He
    a State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education , Guizhou University , Guiyang , PR China.
  • Xiao Li
    Department of Inner Mongolia Clinical Medicine College, Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.
  • Yun Wang
    Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China.
  • Zaiyi Liu
    Department of Radiology, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
  • Longjiang Zhang
    Department of Medical Imaging, Jinling Hospital, Nanjing University School of Medicine, No.305, Zhongshan East Road, Nanjing, 210002, China.
  • Zhengyu Jin
    Departments of Radiology, Peking Union Medical College Hospital, Beijing.
  • Huadan Xue
    From the Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. Electronic address: bjdanna95@163.com.
  • Yizhou Yu
    Department of Computer Science, The University of Hong Kong, Pok Fu Lam, Hong Kong.