Chronic primary adrenal insufficiency after unilateral adrenonephrectomy: A case report.

Journal: Medicine
PMID:

Abstract

RATIONALE: Unilateral adrenalectomy as part of surgical resection of renal cell carcinoma (RCC) is not thought to increase the risk of chronic adrenal insufficiency, as the contralateral adrenal gland is assumed to be capable of compensating for the lost function of the resected gland. However, recent studies have indicated that adrenalectomy might cause irreversible impairment of the adrenocortical reserve. We describe a case of chronic primary adrenal insufficiency in a 68-year-old man who previously underwent unilateral adrenonephrectomy, which was complicated by severe postoperative adrenal stress that involved cardiopulmonary disturbance and systemic infection.

Authors

  • Satoshi Yoshiji
    Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto Department of Medical Genetics, Shizuoka General Hospital, Shizuoka, Japan.
  • Kimitaka Shibue
  • Toshihito Fujii
  • Takeshi Usui
  • Keisho Hirota
  • Daisuke Taura
  • Mayumi Inoue
  • Masakatsu Sone
  • Akihiro Yasoda
  • Nobuya Inagaki