BACKGROUND: Renal cell carcinoma (RCC) is a common, often lethal kidney cancer that originates in the renal cortex. Its incidence is rising, and major factors include smoking, obesity, and hypertension, though its etiology is uncertain. While surgery...
Journal of cancer research and clinical oncology
Dec 16, 2025
BACKGROUND: Clear cell renal cell carcinoma (ccRCC) is a major type of kidney cancer, making up about 80% of cases, with advanced stages showing low survival rates. Current treatments face challenges like toxicity and drug resistance. Studies indicat...
BACKGROUND: Renal cell carcinoma (RCC), which accounts for 70-90% of kidney malignancies, remains difficult to diagnose early due to its asymptomatic onset and the lack of reliable biomarkers. This study aimed to develop a robust diagnostic model by ...
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Dec 3, 2025
Anatomic imaging of renal masses provides limited information on the histology or likely aggressiveness of the tumor, leading to the use of invasive procedures such as renal mass biopsy or empiric partial or radical nephrectomy. Molecular imaging can...
Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell carcinoma (RCC). Although we have made many achievements in the therapy of RCC with the progress of medicine, the clinical management of metastatic RCC remains a dauntin...
Accurate survival prediction is essential for guiding follow-up strategies in patients with cT1b renal cell carcinoma (RCC). Traditional AJCC TNM staging systems provide limited prognostic accuracy. Data from the SEER database were used, which includ...
Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like (APOBEC) cytidine deaminases are a highly evolutionarily conserved protein family. Their members are closely associated with DNA damage repair and involved in the genesis and progressio...
PURPOSE: A deep learning model integrating CT radiomics and clinical features was developed to predict perioperative complications and risk grade in patients undergoing partial nephrectomy, and was compared to traditional anatomical classification mo...
Cancer is a life-threatening disease that affects several human lives all over the world. The classification of cancer severities utilizing histopathological images is vital for effective and timely diagnosis. This always creates a demandable require...
BACKGROUND: Accurate preoperative T and TNM staging of clear cell renal cell carcinoma (ccRCC) is crucial for diagnosis and treatment, but these assessments often depend on subjective radiologist judgment, leading to interobserver variability. This s...
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