Body composition predicts hypertension using machine learning methods: a cohort study.

Journal: Scientific reports
PMID:

Abstract

We used machine learning methods to investigate if body composition indices predict hypertension. Data from a cohort study was used, and 4663 records were included (2156 were male, 1099 with hypertension, with the age range of 35-70 years old). Body composition analysis was done using bioelectrical impedance analysis (BIA); weight, basal metabolic rate, total and regional fat percentage (FATP), and total and regional fat-free mass (FFM) were measured. We used machine learning methods such as Support Vector Classifier, Decision Tree, Stochastic Gradient Descend Classifier, Logistic Regression, Gaussian Naïve Bayes, K-Nearest Neighbor, Multi-Layer Perceptron, Random Forest, Gradient Boosting, Histogram-based Gradient Boosting, Bagging, Extra Tree, Ada Boost, Voting, and Stacking to classify the investigated cases and find the most relevant features to hypertension. FATP, AFFM, BMR, FFM, TRFFM, AFATP, LFATP, and older age were the top features in hypertension prediction. Arm FFM, basal metabolic rate, total FFM, Trunk FFM, leg FFM, and male gender were inversely associated with hypertension, but total FATP, arm FATP, leg FATP, older age, trunk FATP, and female gender were directly associated with hypertension. AutoMLP, stacking and voting methods had the best performance for hypertension prediction achieving an accuracy rate of 90%, 84% and 83%, respectively. By using machine learning methods, we found that BIA-derived body composition indices predict hypertension with acceptable accuracy.

Authors

  • Mohammad Ali Nematollahi
    Department of Computer Sciences, Fasa University, Fasa, Iran.
  • Soodeh Jahangiri
    Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Arefeh Asadollahi
    Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
  • Maryam Salimi
    Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Azizallah Dehghan
    Noncommunicable Disease Research Center, Fasa University of Medical Sciences, Fasa, Iran.
  • Mina Mashayekh
    Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Mohamad Roshanzamir
    Department of Computer Engineering, Faculty of Engineering, Fasa University, Fasa, 74617-81189 Iran.
  • Ghazal Gholamabbas
    Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Roohallah Alizadehsani
    Institute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia.
  • Mehdi Bazrafshan
    Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Zand St, PO Box: 71348-14336, Shiraz, Iran.
  • Hanieh Bazrafshan
    Department of Neurology, Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Hamed Bazrafshan Drissi
    Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Zand St, PO Box: 71348-14336, Shiraz, Iran.
  • Sheikh Mohammed Shariful Islam
    Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia.