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Body Composition

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Improving the prediction of chemotherapy dose-limiting toxicity in colon cancer patients using an AI-CT-based 3D body composition of the entire L1-L5 lumbar spine.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
PURPOSE: Chemotherapy dose-limiting toxicities (DLT) pose a significant challenge in successful colon cancer treatment. Body composition analysis may enable tailored interventions thereby supporting the mitigation of chemotherapy toxic effects. This ...

Assessing the prognostic impact of body composition phenotypes on surgical outcomes and survival in patients with spinal metastasis: a deep learning approach to preoperative CT analysis.

Journal of neurosurgery. Spine
OBJECTIVE: The prognostic significance of body composition phenotypes for survival in patients undergoing surgical intervention for spinal metastases has not yet been elucidated. This study aimed to elucidate the impact of body composition phenotypes...

Artificial intelligence for body composition assessment focusing on sarcopenia.

Scientific reports
This study aimed to address the limitations of conventional methods for measuring skeletal muscle mass for sarcopenia diagnosis by introducing an artificial intelligence (AI) system for direct computed tomography (CT) analysis. The primary focus was ...

CT-Based Body Composition Measures and Systemic Disease: A Population-Level Analysis Using Artificial Intelligence Tools in Over 100,000 Patients.

AJR. American journal of roentgenology
CT-based abdominal body composition measures have shown associations with important health outcomes. Advances in artificial intelligence (AI) now allow deployment of tools that measure body composition in large patient populations. The purpose of t...

Quantification of training-induced alterations in body composition via automated machine learning analysis of MRI images in the thigh region: A pilot study in young females.

Physiological reports
The maintenance of an appropriate ratio of body fat to muscle mass is essential for the preservation of health and performance, as excessive body fat is associated with an increased risk of various diseases. Accurate body composition assessment requi...

Applying Artificial Intelligence to Quantify Body Composition on Abdominal CTs and Better Predict Kidney Transplantation Wait-List Mortality.

Journal of the American College of Radiology : JACR
BACKGROUND: Prekidney transplant evaluation routinely includes abdominal CT for presurgical vascular assessment. A wealth of body composition data are available from these CT examinations, but they remain an underused source of data, often missing fr...

Development and validation of machine learning models for predicting low muscle mass in patients with obesity and diabetes.

Lipids in health and disease
BACKGROUND AND AIMS: Low muscle mass (LMM) is a critical complication in patients with obesity and diabetes, exacerbating metabolic and cardiovascular risks. Novel obesity indices, such as the body roundness index (BRI), conicity index, and relative ...

Validation of body composition parameters extracted via deep learning-based segmentation from routine computed tomographies.

Scientific reports
Sarcopenia and body composition metrics are strongly associated with patient outcomes. In this study, we developed and validated a flexible, open-access pipeline integrating available deep learning-based segmentation models with pre- and postprocessi...

Artificial intelligence generated 3D body composition predicts dose modifications in patients undergoing neoadjuvant chemotherapy for rectal cancer.

Journal of cancer research and clinical oncology
PURPOSE: Chemotherapy administration is a balancing act between giving enough to achieve the desired tumour response while limiting adverse effects. Chemotherapy dosing is based on body surface area (BSA). Emerging evidence suggests body composition ...