Prediction of Fishman's skeletal maturity indicators using artificial intelligence.

Journal: Scientific reports
Published Date:

Abstract

The present study aimed to evaluate the performance of automated skeletal maturation assessment system for Fishman's skeletal maturity indicators (SMI) for the use in dental fields. Skeletal maturity is particularly important in orthodontics for the determination of treatment timing and method. SMI is widely used for this purpose, as it is less time-consuming and practical in clinical use compared to other methods. Thus, the existing automated skeletal age assessment system based on Greulich and Pyle and Tanner-Whitehouse3 methods was further developed to include SMI using artificial intelligence. This hybrid SMI-modified system consists of three major steps: (1) automated detection of region of interest; (2) automated evaluation of skeletal maturity of each region; and (3) SMI stage mapping. The primary validation was carried out using a dataset of 2593 hand-wrist radiographs, and the SMI mapping algorithm was adjusted accordingly. The performance of the final system was evaluated on a test dataset of 711 hand-wrist radiographs from a different institution. The system achieved a prediction accuracy of 0.772 and mean absolute error and root mean square error of 0.27 and 0.604, respectively, indicating a clinically reliable performance. Thus, it can be used to improve clinical efficiency and reproducibility of SMI prediction.

Authors

  • Harim Kim
    Department of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, Seoul, Republic of Korea.
  • Cheol-Soon Kim
    Private Clinic, Seongnam-si, Republic of Korea.
  • Ji-Min Lee
    Department of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, Seoul, Republic of Korea.
  • Jae Joon Lee
    Crescom, Seongnam-si, Republic of Korea.
  • Jiyeon Lee
    Department of Brain and Cognitive Engineering, Korea University, Seoul, Republic of Korea.
  • Jung-Suk Kim
    Private Clinic, Seongnam-si, Republic of Korea. jsofkim@daum.net.
  • Sung-Hwan Choi
    BK21 FOUR Project, Department of Orthodontics, Institute of Craniofacial Deformity, Yonsei University College of Dentistry, 50-1 Yonseiro, Seodaemun-gu, Seoul, 03722, Korea.