Shortwave infrared diffuse optical wearable probe for quantification of water and lipid content in emulsion phantoms using deep learning.

Journal: Journal of biomedical optics
PMID: 37313427

Abstract

SIGNIFICANCE: The shortwave infrared (SWIR, to 2000 nm) holds promise for label-free measurements of water and lipid content in thick tissue, owed to the chromophore-specific absorption features and low scattering in this range. water and lipid estimations have potential applications including the monitoring of hydration, volume status, edema, body composition, weight loss, and cancer. To the best of our knowledge, there are currently no point-of-care or wearable devices available that exploit the SWIR wavelength range, limiting clinical and at-home translation of this technology.

Authors

  • Samuel S Spink
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Anahita Pilvar
    Boston University, Department of Electrical and Computer Engineering, Boston, Massachusetts, United States.
  • Lina Lin Wei
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Jodee Frias
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Kylee Anders
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Sabrina T Franco
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Olivia Claire Rose
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Megan Freeman
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Grace Bag
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Huiru Huang
    Boston University, Department of Biomedical Engineering, Boston, Massachusetts, United States.
  • Darren Roblyer

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