The FeatureCloud Platform for Federated Learning in Biomedicine: Unified Approach.

Journal: Journal of medical Internet research
PMID:

Abstract

BACKGROUND: Machine learning and artificial intelligence have shown promising results in many areas and are driven by the increasing amount of available data. However, these data are often distributed across different institutions and cannot be easily shared owing to strict privacy regulations. Federated learning (FL) allows the training of distributed machine learning models without sharing sensitive data. In addition, the implementation is time-consuming and requires advanced programming skills and complex technical infrastructures.

Authors

  • Julian Matschinske
    Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
  • Julian Späth
    Chair of Computational Systems Biology, University of Hamburg, Hamburg 22607, Germany.
  • Mohammad Bakhtiari
    University of Hamburg, Hamburg, Germany.
  • Niklas Probul
    University of Hamburg, Hamburg, Germany.
  • Mohammad Mahdi Kazemi Majdabadi
    University of Hamburg, Hamburg, Germany.
  • Reza Nasirigerdeh
    Technical University Munich, Munich, Germany.
  • Reihaneh Torkzadehmahani
    Technical University Munich, Munich, Germany.
  • Anne Hartebrodt
    University of Southern Denmark, Odense, Denmark.
  • Balazs-Attila Orban
    Gnome Design SRL, Sfântu Gheorghe, Romania.
  • Sándor-József Fejér
    Gnome Design SRL, Sfântu Gheorghe, Romania.
  • Olga Zolotareva
    International Research Training Group Computational Methods for the Analysis of the Diversity and Dynamics of Genomes and Genome Informatics, Faculty of Technology and Center for Biotechnology, Bielefeld University, Germany.
  • Supratim Das
    University of Hamburg, Hamburg, Germany.
  • Linda Baumbach
    University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Josch K Pauling
    LipiTUM, Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
  • Olivera Tomašević
    University of Novi Sad, Novi Sad, .
  • Béla Bihari
    Gnome Design SRL, Sfântu Gheorghe, Romania.
  • Marcus Bloice
    Medical University of Graz, Graz, Austria.
  • Nina C Donner
    Concentris Research Management gGmbH, Fürstenfeldbruck, Germany.
  • Walid Fdhila
    SBA Research gGmbH, Vienna, Austria.
  • Tobias Frisch
    University of Southern Denmark, Odense, Denmark.
  • Anne-Christin Hauschild
    IBM Life Sciences Discovery Centre, Princess Margaret Cancer Centre, Toronto, ON, Canada; Department of Computer Science, University of Toronto, Toronto, ON, Canada; University Health Network, Toronto, ON, Canada.
  • Dominik Heider
    Department of Mathematics and Computer Science, University of Marburg, Marburg, Germany.
  • Andreas Holzinger
    Human-Centered AI Lab, Medical University of Graz, Graz, Austria.
  • Walter Hötzendorfer
    Research Institute AG & Co KG, Vienna, Austria.
  • Jan Hospes
    Research Institute AG & Co KG, Vienna, Austria.
  • Tim Kacprowski
    Interfaculty Institute for Genetics and Functional Genomics, University Medicine and University of Greifswald, Greifswald, Germany.
  • Markus Kastelitz
    Research Institute AG & Co KG, Vienna, Austria.
  • Markus List
    Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
  • Rudolf Mayer
    SBA Research gGmbH, Vienna, Austria.
  • Mónika Moga
    Gnome Design SRL, Sfântu Gheorghe, Romania.
  • Heimo Müller
    Medical University of Graz, Graz, Austria.
  • Anastasia Pustozerova
    SBA Research gGmbH, Vienna, Austria.
  • Richard Röttger
    Department of Mathematics and Computer Science, University of Southern Denmark, Odense, Denmark.
  • Christina C Saak
    University of Hamburg, Hamburg, Germany.
  • Anna Saranti
    Human-Centered AI Lab, Institute of Forest Engineering, Department of Forest and Soil Sciences, University of Natural Resources and Life Sciences Vienna, 1190 Wien, Austria.
  • Harald H H W Schmidt
    Maastricht University, Maastricht, Netherlands.
  • Christof Tschohl
    Research Institute AG & Co KG, Vienna, Austria.
  • Nina K Wenke
    Chair of Experimental Bioinformatics, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
  • Jan Baumbach
    TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.