Padé approximant meets federated learning: A nearly lossless, one-shot algorithm for evidence synthesis in distributed research networks with rare outcomes.

Journal: Journal of biomedical informatics
Published Date:

Abstract

OBJECTIVE: We developed and evaluated a novel one-shot distributed algorithm for evidence synthesis in distributed research networks with rare outcomes.

Authors

  • Qiong Wu
    Key Laboratory of Flexible Electronics (KLOFE) and Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, P. R. China.
  • Martijn J Schuemie
    Janssen Research and Development, Raritan, NJ, USA.
  • Marc A Suchard
    Department of Biomathematics, UCLA School of Medicine, CA, USA.
  • Patrick Ryan
    Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • George M Hripcsak
    Department of Biomedical Informatics, Columbia University Irving Medical Center, New York, NY, United States of America; Medical Informatics Services, New York-Presbyterian Hospital, New York, NY, United States of America.
  • Charles A Rohde
    Department of Biostatistics, Johns Hopkins University, Baltimore, MD, United States of America.
  • Yong Chen
    Department of Urology, Chongqing University Fuling Hospital, Chongqing, China.