An interpretable deep learning framework for predicting liver metastases in postoperative colorectal cancer patients using natural language processing and clinical data integration.

Journal: Cancer medicine
Published Date:

Abstract

BACKGROUND: The significance of liver metastasis (LM) in increasing the risk of death for postoperative colorectal cancer (CRC) patients necessitates innovative approaches to predict LM.

Authors

  • Jia Li
    Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan Tsuihang New District, Guangdong, 528400, PR China; School of Pharmacy, Zunyi Medical University, Zunyi, 563000, PR China; National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, PR China.
  • Xinghao Wang
    Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
  • Linkun Cai
    College of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Jing Sun
    Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Zhenghan Yang
    Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
  • Wenjuan Liu
    College of Materials Science and Engineering , Nanjing Tech University , Nanjing , Jiangsu 211816 , China.
  • Zhenchang Wang
    School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
  • Han Lv
    Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.