An APRI+ALBI-Based Multivariable Model as a Preoperative Predictor for Posthepatectomy Liver Failure.

Journal: Annals of surgery
PMID: 37860868

Abstract

OBJECTIVE AND BACKGROUND: Clinically significant posthepatectomy liver failure (PHLF B+C) remains the main cause of mortality after major hepatic resection. This study aimed to establish an aspartate aminotransferase to platelet ratio combined with an albumin-bilirubin grade (APRI+ALBI), based multivariable model (MVM) to predict PHLF and compare its performance to indocyanine green clearance (ICG-R15 or ICG-PDR) and albumin-ICG evaluation (ALICE).

Authors

  • Jonas Santol
    Department of Surgery, HPB Center, Vienna Health Network, Clinic Favoriten and Sigmund Freud Private University, Vienna, Austria.
  • Sarang Kim
    Medical University of Vienna, Vienna, Austria.
  • Lindsey A Gregory
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • Ruth Baumgartner
    Department of Oncology, Karolinska University Hospital, Stockholm, Sweden.
  • Anastasia Murtha-Lemekhova
    Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
  • Emrullah Birgin
    Chirurgische Klinik, Universitätsklinikum Mannheim, Mannheim, Deutschland.
  • Severin Gloor
    Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Eva Braunwarth
    Department of Visceral, Transplantation and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
  • Markus Ammann
    Department of Surgery, State Hospital Wiener Neustadt, Wiener Neustadt, Austria.
  • Johannes Starlinger
    Howto Health GmbH, Berlin, Germany.
  • David Pereyra
    Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna, Austria.
  • Daphni Ammon
    Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna, Austria.
  • Marijana Ninkovic
    Department of Visceral, Transplantation and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
  • Anna E Kern
    Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Vienna, Austria.
  • Benedikt Rumpf
    Department of Surgery, Hospital Barmherzige Schwestern, Vienna, Austria.
  • Gregor Ortmayr
    Center for Cancer Research, Medical University of Vienna, Vienna, Austria.
  • Yannic Herrmann
    Medical University of Vienna, Vienna, Austria.
  • Yawen Dong
    Department of Surgery, HPB Center, Vienna Health Network, Clinic Favoriten and Sigmund Freud Private University, Vienna, Austria.
  • Felix X Huber
    Medical University of Vienna, Vienna, Austria.
  • Jeremias Weninger
    Medical University of Vienna, Vienna, Austria.
  • Cornelius A Thiels
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • Susanne G Warner
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • Rory L Smoot
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • Mark J Truty
    Department of General and Gastrointestinal Surgery, Mayo Clinic, 200 First Street SW, MN, 55905, USA.
  • Michael L Kendrick
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • David M Nagorney
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • Sean P Cleary
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MN, USA.
  • Guido Beldi
    Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
  • Nuh N Rahbari
    Chirurgische Klinik, Universitätsklinikum Mannheim, Mannheim, Deutschland.
  • Katrin Hoffmann
    Department of General, Visceral, and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany.
  • Stefan Gilg
    Department of HPB surgery, Karolinska University Hospital, Stockholm, Sweden.
  • Alice Assinger
    Institute of Vascular Biology and Thrombosis Research, Center of Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
  • Thomas Gruenberger
    Department of Surgery, HPB Center, Vienna Health Network, Clinic Favoriten and Sigmund Freud Private University, Vienna, Austria.
  • Hubert Hackl
    Institute of Bioinformatics, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
  • Patrick Starlinger
    Department of Surgery, Division of Hepatobiliary and Pancreas Surgery, Mayo Clinic, Rochester, MA, USA.

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