EGeRepDR: An enhanced genetic-based representation learning for drug repurposing using multiple biomedical sources.
Journal:
Journal of biomedical informatics
Published Date:
Oct 18, 2023
Abstract
MOTIVATION: Drug repurposing (DR) is an imminent approach for identifying novel therapeutic indications for the available drugs and discovering novel drugs for previously untreatable diseases. Nowadays, DR has major attention in the pharmaceutical industry due to the high cost and time of launching new drugs to the market through traditional drug development. DR task majorly depends on genetic information since the drugs revert the modified Gene Expression (GE) of diseases to normal. Many of the existing studies have not considered the genetic importance of predicting the potential candidates.