GPDRP: a multimodal framework for drug response prediction with graph transformer.
Journal:
BMC bioinformatics
Published Date:
Dec 17, 2023
Abstract
BACKGROUND: In the field of computational personalized medicine, drug response prediction (DRP) is a critical issue. However, existing studies often characterize drugs as strings, a representation that does not align with the natural description of molecules. Additionally, they ignore gene pathway-specific combinatorial implication.