Predicting Antiseizure Medication Treatment in Children with Rare Tuberous Sclerosis Complex-Related Epilepsy Using Deep Learning.

Journal: AJNR. American journal of neuroradiology
PMID:

Abstract

BACKGROUND AND PURPOSE: Tuberous sclerosis complex disease is a rare, multisystem genetic disease, but appropriate drug treatment allows many pediatric patients to have positive outcomes. The purpose of this study was to predict the effectiveness of antiseizure medication treatment in children with tuberous sclerosis complex-related epilepsy.

Authors

  • Haifeng Wang
    Collaborative Innovation Center of Seafood Deep Processing, Institute of Seafood, Zhejiang Gongshang University, Hangzhou, 310012, China.
  • Zhanqi Hu
    Department of Neurology (Z.H., R.L., X.Z., J.L.), Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
  • Dian Jiang
    From the Research Center for Medical Artificial Intelligence (H.W., D.J., Y. Zhou, D.L., Z.L.), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
  • Rongbo Lin
    Department of Neurology (Z.H., R.L., X.Z., J.L.), Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
  • Cailei Zhao
    Department of Radiology (C.Z., H.Z.), Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
  • Xia Zhao
    Stony Brook University, Stony Brook, NY.
  • Yihang Zhou
    From the Research Center for Medical Artificial Intelligence (H.W., D.J., Y. Zhou, D.L., Z.L.), Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
  • Yanjie Zhu
    Paul C. Lauterbur Research Centre for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Shenzhen, Guangdong, China.
  • Hongwu Zeng
    Department of Radiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, People's Republic of China. homerzeng@126.com.
  • Dong Liang
    Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055 China.
  • Jianxiang Liao
    Department of Neurology (Z.H., R.L., X.Z., J.L.), Shenzhen Children's Hospital, Shenzhen, Guangdong, China liaojianxiang@vip.sina.com.
  • Zhicheng Li
    Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.