Applicability and robustness of an artificial intelligence-based assessment for Greulich and Pyle bone age in a German cohort.

Journal: RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
PMID:

Abstract

PURPOSE: The determination of bone age (BA) based on the hand and wrist, using the 70-year-old Greulich and Pyle (G&P) atlas, remains a widely employed practice in various institutions today. However, a more recent approach utilizing artificial intelligence (AI) enables automated BA estimation based on the G&P atlas. Nevertheless, AI-based methods encounter limitations when dealing with images that deviate from the standard hand and wrist projections. Generally, the extent to which BA, as determined by the G&P atlas, corresponds to the chronological age (CA) of a contemporary German population remains a subject of continued discourse. This study aims to address two main objectives. Firstly, it seeks to investigate whether the G&P atlas, as applied by the AI software, is still relevant for healthy children in Germany today. Secondly, the study aims to assess the performance of the AI software in handling non-strict posterior-anterior (p. a.) projections of the hand and wrist.

Authors

  • Johanna Pape
    Pediatric Radiology, University Hospital Leipzig, Germany.
  • Franz Wolfgang Hirsch
    Pediatric Radiology, University Hospital Leipzig, Germany.
  • Oliver Johannes Deffaa
    Pediatric Surgery, University Hospital Leipzig, Germany.
  • Matthew D DiFranco
    Image Biopsy Lab GmbH, Zehetnergasse 6/2/2, 1140, Vienna, Austria.
  • Maciej Rosolowski
    Image Biopsy Lab GmbH, Vienna, Austria.
  • Daniel Gräfe
    Department of Pediatric Radiology, University Hospital, Leipzig, Germany. daniel.graefe@medizin.uni-leipzig.de.