A neural network approach to predict opioid misuse among previously hospitalized patients using electronic health records.

Journal: PloS one
Published Date:

Abstract

Can Electronic Health Records (EHR) predict opioid misuse in general patient populations? This research trained three backpropagation neural networks to explore EHR predictors using existing patient data. Model 1 used patient diagnosis codes and was 75.5% accurate. Model 2 used patient prescriptions and was 64.9% accurate. Model 3 used both patient diagnosis codes and patient prescriptions and was 74.5% accurate. This suggests patient diagnosis codes are best able to predict opioid misuse. Opioid misusers have higher rates of drug abuse/mental health disorders than the general population, which could explain the performance of diagnosis predictors. In additional testing, Model 1 misclassified only 1.9% of negative cases (non-abusers), demonstrating a low type II error rate. This suggests further clinical implementation is viable. We hope to motivate future research to explore additional methods for universal opioid misuse screening.

Authors

  • Lucas Vega
    Data Analytics Lab, The University of Texas at Tyler, Tyler, Texas, United States of America.
  • Winslow Conneen
    Data Analytics Lab, The University of Texas at Tyler, Tyler, Texas, United States of America.
  • Michael A Veronin
    Pharmaceutical Sciences Department, The University of Texas at Tyler, Tyler, Texas, United States of America.
  • Robert P Schumaker
    Computer Science Department, The University of Texas at Tyler, Tyler, Texas, United States of America.