Screening Targets and Therapeutic Drugs for Alzheimer's Disease Based on Deep Learning Model and Molecular Docking.

Journal: Journal of Alzheimer's disease : JAD
Published Date: Jan 1, 2024

Abstract

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder caused by a complex interplay of various factors. However, a satisfactory cure for AD remains elusive. Pharmacological interventions based on drug targets are considered the most cost-effective therapeutic strategy. Therefore, it is paramount to search potential drug targets and drugs for AD.

Authors

  • Ya-Hong Zhang
    College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Pu Zhao
    College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Hui-Ling Gao
    College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Man-Li Zhong
    College of Life and Health Sciences, Northeastern University, Shenyang, China.
  • Jia-Yi Li
    Health Sciences Institute, China Medical University, Shenyang, China.

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