Developing effective treatments for Alzheimer's disease (AD) likely requires a deep understanding of molecular mechanisms. Integration of transcriptomic datasets and developing innovative computational analyses may yield novel molecular targets with ...
American journal of Alzheimer's disease and other dementias
40322901
To improve the identification of cognitive impairment by distinguishing normal cognition (NC), mild cognitive impairment (MCI), and Alzheimer's disease (AD). A recursive partitioning tree model was developed using ARMADA data and the NIH Toolbox, a...
Alzheimer's & dementia : the journal of the Alzheimer's Association
40356024
INTRODUCTION: Alzheimer's disease (AD), a leading cause of dementia, requires early detection for effective intervention. This study employs AI to analyze multimodal datasets, including clinical, biomarker, and neuroimaging data, using hybrid deep le...
The rapid growth of multi-omics datasets and the wealth of biological knowledge necessitates the development of effective methods for their integration. Such methods are essential for building predictive models and identifying drug targets based on a...
In the context of lifestyle changes, stress and other environmental factors have resulted in the sudden hike in dementia globally. This necessitates investigations with respect to every horizon of the due cause for it; further on, the diagnosis and t...
BACKGROUND: Accurate genetic risk prediction and understanding the mechanisms underlying complex diseases are essential for effective intervention and precision medicine. However, current methods often struggle to capture the intricate and subtle gen...
Alzheimer's disease (AD) is a neurodegenerative disorder that affects memory and cognitive functions. Manual diagnosis is prone to human error, often leading to misdiagnosis or delayed detection. MRI techniques help visualize the fine tissues of the ...
BACKGROUND: Exploring the early stages of Alzheimer's disease (AD) is crucial for timely intervention to help manage symptoms and set expectations for affected individuals and their families. However, the study of the early stages of AD involves anal...
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely affects memory, behavior, and cognitive function. Early and accurate diagnosis is crucial for effective intervention, yet detecting subtle changes in the early stages ...
Dementia spectrum disorders, characterized by progressive cognitive decline, pose a significant global health burden. Early screening and diagnosis are essential for timely and accurate treatment, improving patient outcomes and quality of life. This ...