Identification of high-risk imaging features in hypertrophic cardiomyopathy using electrocardiography: A deep-learning approach.

Journal: Heart rhythm
Published Date:

Abstract

BACKGROUND: Patients with hypertrophic cardiomyopathy (HCM) are at risk of sudden death, and individuals with ≥1 major risk markers are considered for primary prevention implantable cardioverter-defibrillators. Guidelines recommend cardiac magnetic resonance (CMR) imaging to identify high-risk imaging features. However, CMR imaging is resource intensive and is not widely accessible worldwide.

Authors

  • Richard T Carrick
    Division of Cardiology, Johns Hopkins University Department of Medicine, Baltimore, Maryland, USA.
  • Hisham Ahamed
    Amrita Institute of Medical Sciences and Research Centre, Amrita Hypertrophic Cardiomyopathy Center, Kochi, Kerala, India.
  • Eric Sung
    Department of Biomedical Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA.
  • Martin S Maron
  • Christopher Madias
    Tufts Medical Center, Cardiac Arrhythmia Center, Boston, Massachusetts.
  • Vennela Avula
    Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Rachael Studley
    Tufts Medical Center, Cardiac Arrhythmia Center, Boston, Massachusetts.
  • Chen Bao
    Tufts Medical Center, Cardiac Arrhythmia Center, Boston, Massachusetts.
  • Nadia Bokhari
    Tufts Medical Center, Cardiac Arrhythmia Center, Boston, Massachusetts.
  • Erick Quintana
    Tufts Medical Center, Cardiac Arrhythmia Center, Boston, Massachusetts.
  • Ramiah Rajesh-Kannan
    Amrita Institute of Medical Sciences and Research Centre, Amrita Hypertrophic Cardiomyopathy Center, Kochi, Kerala, India.
  • Barry J Maron
    Lahey Hospital and Medical Center, Hypertrophic Cardiomyopathy Center, Burlington, Massachusetts.
  • Katherine C Wu
    Division of Cardiology, Johns Hopkins University Department of Medicine, Baltimore, Maryland, USA.
  • Ethan J Rowin
    From the Departments of Medicine (Cardiovascular Division) (A.S.F., U.N., W.J.M., R.N.) and Radiology (W.J.M.), Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Ave, Boston, MA 02215; Toronto General Hospital, University Health Network, Toronto, Ontario, Canada (R.H.C.); and Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, Boston, Mass (E.J.R., M.S.M.).