AI-Enhanced Detection of Clinically Relevant Structural and Functional Anomalies in MRI: Traversing the Landscape of Conventional to Explainable Approaches.

Journal: Journal of magnetic resonance imaging : JMRI
Published Date:

Abstract

Anomaly detection in medical imaging, particularly within the realm of magnetic resonance imaging (MRI), stands as a vital area of research with far-reaching implications across various medical fields. This review meticulously examines the integration of artificial intelligence (AI) in anomaly detection for MR images, spotlighting its transformative impact on medical diagnostics. We delve into the forefront of AI applications in MRI, exploring advanced machine learning (ML) and deep learning (DL) methodologies that are pivotal in enhancing the precision of diagnostic processes. The review provides a detailed analysis of preprocessing, feature extraction, classification, and segmentation techniques, alongside a comprehensive evaluation of commonly used metrics. Further, this paper explores the latest developments in ensemble methods and explainable AI, offering insights into future directions and potential breakthroughs. This review synthesizes current insights, offering a valuable guide for researchers, clinicians, and medical imaging experts. It highlights AI's crucial role in improving the precision and speed of detecting key structural and functional irregularities in MRI. Our exploration of innovative techniques and trends furthers MRI technology development, aiming to refine diagnostics, tailor treatments, and elevate patient care outcomes. LEVEL OF EVIDENCE: 5 TECHNICAL EFFICACY: Stage 1.

Authors

  • Pegah Khosravi
    Institute for Computational Biomedicine, Weill Cornell Medical College, NY, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY, USA.
  • Saber Mohammadi
    Department of Biological Sciences, New York City College of Technology, CUNY, New York City, New York, USA.
  • Fatemeh Zahiri
    Department of Cell and Molecular Sciences, Kharazmi University, Tehran, Iran.
  • Masoud Khodarahmi
    Bahar Medical Imaging Center, Karaj, Iran.
  • Javad Zahiri
    Department of Neuroscience, University of California San Diego, La Jolla, CA, USA. jzahiri@health.ucsd.edu.