Role of the Neurologic System in Fracture Healing: An Extensive Review.

Journal: Current osteoporosis reports
PMID:

Abstract

PURPOSE OF REVIEW: Despite advances in orthopedics, there remains a need for therapeutics to hasten fracture healing. However, little focus is given to the role the nervous system plays in regulating fracture healing. This paucity of information has led to an incomplete understanding of fracture healing and has limited the development of fracture therapies that integrate the importance of the nervous system. This review seeks to illuminate the integral roles that the nervous system plays in fracture healing.

Authors

  • Reginald S Parker
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Murad K Nazzal
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Ashlyn J Morris
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Jill C Fehrenbacher
    Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Fletcher A White
    Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN, USA. fawhite@iu.edu.
  • Melissa A Kacena
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. mkacena@iupui.edu.
  • Roman M Natoli
    Department of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.