Automated Prediction of Photographic Wound Assessment Tool in Chronic Wound Images.

Journal: Journal of medical systems
Published Date:

Abstract

Many automated approaches have been proposed in literature to quantify clinically relevant wound features based on image processing analysis, aiming at removing human subjectivity and accelerate clinical practice. In this work we present a fully automated image processing pipeline leveraging deep learning and a large wound segmentation dataset to perform wound detection and following prediction of the Photographic Wound Assessment Tool (PWAT), automatizing the clinical judgement of the adequate wound healing. Starting from images acquired by smartphone cameras, a series of textural and morphological features are extracted from the wound areas, aiming to mimic the typical clinical considerations for wound assessment. The resulting extracted features can be easily interpreted by the clinician and allow a quantitative estimation of the PWAT scores. The features extracted from the region-of-interests detected by our pre-trained neural network model correctly predict the PWAT scale values with a Spearman's correlation coefficient of 0.85 on a set of unseen images. The obtained results agree with the current state-of-the-art and provide a benchmark for future artificial intelligence applications in this research field.

Authors

  • Nico Curti
    Department of Specialised, Diagnostic and Experimental Medicine, University of Bologna, 40126, Bologna, BO, Italy.
  • Yuri Merli
    Dermatology, IRCCS Sant'Orsola-Malpighi Hospital, 40138 Bologna, Italy.
  • Corrado Zengarini
    Dermatology, IRCCS Sant'Orsola-Malpighi Hospital, 40138 Bologna, Italy.
  • Michela Starace
    Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
  • Luca Rapparini
    Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.
  • Emanuela Marcelli
    Department of Experimental, Diagnostic and Specialty Medicine (DIMES), Laboratory of Bioengineering, University of Bologna, Bologna, Italy.
  • Gianluca Carlini
    Data Science and Bioinformatics Laboratory, IRCCS Institute of Neurological Sciences of Bologna, 40139, Bologna, Italy.
  • Daniele Buschi
    Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.
  • Gastone C Castellani
    Department of Medical and Surgical Sciences, University of Bologna, 40138, Bologna, Italy.
  • Bianca Maria Piraccini
    Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
  • Tommaso Bianchi
    Dermatology, IRCCS Sant'Orsola-Malpighi Hospital, 40138 Bologna, Italy.
  • Enrico Giampieri
    Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.