Effect and Safety of Diluted Vasopressin Injection for Bleeding Control During Robot-assisted Laparoscopic Myomectomy in Reproductive Women With Uterine Fibroids: A Randomized Controlled Pilot Trial (VALENTINE Trial).

Journal: In vivo (Athens, Greece)
Published Date: Jan 1, 2024

Abstract

BACKGROUND/AIM: Vasopressin injected during myomectomy is known to effectively reduce bleeding but is sometimes associated with intraoperative vasoconstriction and hypertension due to systemic absorption. Although there is a growing preference for the use of diluted vasopressin, evidence of its effect and safety is still lacking.

Authors

  • Soo Jin Park
    Department of Obstetrcis and Gynecology, Seoul National University Hospital, Seoul, Korea (the Republic of).
  • Joo Won Lee
    Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
  • Dong Won Hwang
    Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Republic of Korea.
  • Seungmee Lee
    Department of Obstetrics and Gynecology, Keimyung University School of Medicine, Daegu, Korea (the Republic of).
  • Ga Won Yim
    Department of Obstetrics and Gynecology, Institute of Women's Medical Life Science, Yonsei University College of Medicine, Seoul, Korea.
  • Gwonhwa Song
    Institute of Animal Molecular Biotechnology and Department of Biotechnology, Korea University, Seoul, Korea (the Republic of).
  • Eun Ji Lee
    Department of Pathology, Green Cross Laboratories, Yongin, Gyeonggi, South Korea.
  • Hee Seung Kim
    Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea (the Republic of) bboddi0311@snu.ac.kr.

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