Freezing of gait assessment with inertial measurement units and deep learning: effect of tasks, medication states, and stops.

Journal: Journal of neuroengineering and rehabilitation
Published Date:

Abstract

BACKGROUND: Freezing of gait (FOG) is an episodic and highly disabling symptom of Parkinson's Disease (PD). Traditionally, FOG assessment relies on time-consuming visual inspection of camera footage. Therefore, previous studies have proposed portable and automated solutions to annotate FOG. However, automated FOG assessment is challenging due to gait variability caused by medication effects and varying FOG-provoking tasks. Moreover, whether automated approaches can differentiate FOG from typical everyday movements, such as volitional stops, remains to be determined. To address these questions, we evaluated an automated FOG assessment model with deep learning (DL) based on inertial measurement units (IMUs). We assessed its performance trained on all standardized FOG-provoking tasks and medication states, as well as on specific tasks and medication states. Furthermore, we examined the effect of adding stopping periods on FOG detection performance.

Authors

  • Po-Kai Yang
  • Benjamin Filtjens
    eMedia Research Lab/STADIUS, Department of Electrical Engineering (ESAT), KU Leuven, Andreas Vesaliusstraat 13, 3000 Leuven, Belgium; Intelligent Mobile Platform Research Group, Department of Mechanical Engineering, KU Leuven, Andreas Vesaliusstraat 13, 3000 Leuven, Belgium. Electronic address: benjamin.filtjens@kuleuven.be.
  • Pieter Ginis
  • Maaike Goris
  • Alice Nieuwboer
    Research Group for Neurorehabilitation (eNRGy), Department of Rehabilitation Sciences, KU Leuven, Tervuursevest 101, 3001 Heverlee, Belgium.
  • Moran Gilat
  • Peter Slaets
    Intelligent Mobile Platform Research Group, Department of Mechanical Engineering, KU Leuven, Andreas Vesaliusstraat 13, 3000 Leuven, Belgium.
  • Bart Vanrumste
    eMedia Research Lab/STADIUS, Department of Electrical Engineering (ESAT), KU Leuven, Andreas Vesaliusstraat 13, 3000 Leuven, Belgium.