An indirect estimation of x-ray spectrum via convolutional neural network and transmission measurement.

Journal: Physics in medicine and biology
Published Date:

Abstract

In this work, we aim to propose an accurate and robust spectrum estimation method by synergistically combining x-ray imaging physics with a convolutional neural network (CNN).The approach relies on transmission measurements, and the estimated spectrum is formulated as a convolutional summation of a few model spectra generated using Monte Carlo simulation. The difference between the actual and estimated projections is utilized as the loss function to train the network. We contrasted this approach with the weighted sums of model spectra approach previously proposed. Comprehensive studies were performed to demonstrate the robustness and accuracy of the proposed approach in various scenarios.The results show the desirable accuracy of the CNN-based method for spectrum estimation. The ME and NRMSE were -0.021 keV and 3.04% for 80 kVp, and 0.006 keV and 4.44% for 100 kVp, superior to the previous approach. The robustness test and experimental study also demonstrated superior performances. The CNN-based approach yielded remarkably consistent results in phantoms with various material combinations, and the CNN-based approach was robust concerning spectrum generators and calibration phantoms.. We proposed a method for estimating the real spectrum by integrating a deep learning model with real imaging physics. The results demonstrated that this method was accurate and robust in estimating the spectrum, and it is potentially helpful for broad x-ray imaging tasks.

Authors

  • Tie Lv
    School of Physics, Beihang University, Beijing, People's Republic of China.
  • Shouping Xu
    Department of Radiotherapy, First Medical Center of PLA General Hospital, BeiJing 100853, P.R.China.
  • Yanxin Wang
    School of Physics, Beihang University, Beijing, People's Republic of China.
  • Gaolong Zhang
    School of Physics, Beihang University, Beijing, People's Republic of China.
  • Tianye Niu
    Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
  • Chunyan Liu
    Chengdu Kuafu Technology Co., Ltd., Chengdu 610100, China.
  • Baohua Sun
    School of Physics, Beihang University, Beijing, People's Republic of China.
  • Lisheng Geng
    School of Physics, Beihang University, Beijing, People's Republic of China.
  • Lihua Zhu
    School of Physics, Beihang University, Beijing, People's Republic of China.
  • Wei Zhao
    Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, Jiangnan University, Wuxi 214122, Jiangsu Province, P. R. China. lxy@jiangnan.edu.cn zhuye@jiangnan.edu.cn.