IU-Net: A dual-path U-Net with rich information interaction for medical image segmentation.

Journal: Medical image analysis
Published Date:

Abstract

Although the U-shape networks have achieved remarkable performances in many medical image segmentation tasks, they rarely model the sequential relationship of hierarchical layers. This weakness makes it difficult for the current layer to effectively utilize the historical information of the previous layer, leading to unsatisfactory segmentation results for lesions with blurred boundaries and irregular shapes. To solve this problem, we propose a novel dual-path U-Net, dubbed IU-Net. The newly proposed network encourages historical information re-usage and re-exploration through rich information interaction among the dual paths, allowing deep layers to learn more comprehensive features that contain both low-level detail description and high-level semantic abstraction. Specifically, we introduce a multi-functional information interaction module (MFII), which can model cross-path, cross-layer, and cross-path-and-layer information interactions via a unified design, making the proposed IU-Net behave similarly to an unfolded RNN and enjoying its advantage of modeling time sequence information. Besides, to further selectively and sensitively integrate the information extracted by the encoder of the dual paths, we propose a holistic information fusion and augmentation module (HIFA), which can efficiently bridge the encoder and the decoder. Extensive experiments on four challenging tasks, including skin lesion, polyp, brain tumor, and abdominal multi-organ segmentation, consistently show that the proposed IU-Net has superior performance and generalization ability over other state-of-the-art methods. The code is available at https://github.com/duweidai/I2U-Net.

Authors

  • Duwei Dai
    Institute of Medical Artificial Intelligence, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
  • Caixia Dong
    Institute of Medical Artificial Intelligence, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
  • Qingsen Yan
  • Yongheng Sun
    School of Mathematics and Statistics, Xi'an Jiaotong University, Xi'an 710049, China.
  • Chunyan Zhang
  • Zongfang Li
    Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
  • Songhua Xu
    Institute of Medical Artificial Intelligence, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China. Electronic address: songhua_xu1@163.com.