Deep learning-based classification of erosion, synovitis and osteitis in hand MRI of patients with inflammatory arthritis.

Journal: RMD open
PMID:

Abstract

OBJECTIVES: To train, test and validate the performance of a convolutional neural network (CNN)-based approach for the automated assessment of bone erosions, osteitis and synovitis in hand MRI of patients with inflammatory arthritis.

Authors

  • Maja Schlereth
    Department of Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany maja.schlereth@fau.de.
  • Melek Yalcin Mutlu
    Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Jonas Utz
    Department AIBE, FAU Erlangen-Nürnberg, Germany.
  • Sara Bayat
    Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Tobias Heimann
  • Jingna Qiu
  • Chris Ehring
    Institute of Radiology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Chang Liu
    Key Lab of Cell Differentiation and Apoptosis of Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
  • Michael Uder
    Institute of Radiology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Arnd Kleyer
    Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
  • David Simon
    Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Frank Roemer
    Department of Radiology, University of Erlangen - Nuremberg, Erlangen, Germany; Department of Radiology, Boston University School of Medicine, MA, USA. Electronic address: frank.roemer@uk-erlangen.de.
  • Georg Schett
    Department of Internal Medicine 3-Rheumatology and Immunology, FAU Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Katharina Breininger
  • Filippo Fagni
    Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen, Ulmenweg 18, 91054, Erlangen, Germany.