Distribution-informed and wavelength-flexible data-driven photoacoustic oximetry.

Journal: Journal of biomedical optics
PMID: 38841431

Abstract

SIGNIFICANCE: Photoacoustic imaging (PAI) promises to measure spatially resolved blood oxygen saturation but suffers from a lack of accurate and robust spectral unmixing methods to deliver on this promise. Accurate blood oxygenation estimation could have important clinical applications from cancer detection to quantifying inflammation.

Authors

  • Janek Gröhl
    German Cancer Research Center (DKFZ), Division of Computer Assisted Medical Interventions (CAMI), He, Germany.
  • Kylie Yeung
    University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Kevin Gu
    University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Thomas R Else
    University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Monika Golinska
    University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Ellie V Bunce
    University of Cambridge, Cancer Research UK Cambridge Institute, Cambridge, United Kingdom.
  • Lina Hacker
    Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.
  • Sarah E Bohndiek
    Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, CB2 0RE, UK.

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