CLADSI: Deep Continual Learning for Alzheimer's Disease Stage Identification Using Accelerometer Data.

Journal: IEEE journal of biomedical and health informatics
Published Date:

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder that can cause a significant impairment in physical and cognitive functions. Gait disturbances are also reported as a symptom of AD. Previous works have used Convolutional Neural Networks (CNNs) to analyze data provided by motion sensors that monitor Alzheimer's patients. However, these works have not explored continual learning algorithms that allow the CNN to configure itself as it receives new data from these sensors. This work proposes a method aimed at enabling CNNs to learn from a continuous stream of data from motion sensors without having full access to previous data. The CNN identifies the stage of AD from the analysis of data provided by motion sensors. The work includes an experimentation with data captured by accelerometers that monitored the activity of 35 Alzheimer's patients for a week in a daycare center. The CNN achieves an accuracy of 86,94%, 86,48% and 84,37% for 2, 3 and 4 experiences respectively. The proposal provides advantages to working with a continuous stream of data so that the CNN are constantly self-configuring without the intervention of a human. The work can be considered as promising and helpful in finding deep learning solutions in medical cases in which patients are constantly monitored.

Authors

  • Santos Bringas
    Fundación Centro Tecnológico de Componentes CTC, 39011 Santander, Spain. Electronic address: sbringas@centrotecnologicoctc.com.
  • Rafael Duque
    Department of Mathematics, Statistics and Computer Science, Universidad de Cantabria, 39005 Santander, Spain. Electronic address: rafael.duque@unican.es.
  • Carmen Lage
    Cognitive Disorders Unit, Department of Neurology, Marqués de Valdecilla University Hospital (HUMV), Valdecilla Biomedical Research Institute (IDIVAL), 39008 Santander, Spain. Electronic address: clage@idival.org.
  • José Luis Montaña
    Department of Mathematics, Statistics and Computer Science, Universidad de Cantabria, 39005 Santander, Spain. Electronic address: joseluis.montana@unican.es.