AI Medical Compendium Journal:
Chemistry (Weinheim an der Bergstrasse, Germany)

Showing 1 to 5 of 5 articles

Target Fisher: A Consensus Structure-Based Target Prediction Tool, and its Application in the Discovery of Selective MAO-B Inhibitors.

Chemistry (Weinheim an der Bergstrasse, Germany)
In this work we introduce Target Fisher, a consensus structure-based target prediction tool that integrates molecular docking and machine learning with the aim to aid in the identification of potential biological targets and the optimization of the u...

Application of Machine Learning Algorithms to Metadynamics for the Elucidation of the Binding Modes and Free Energy Landscape of Drug/Target Interactions: a Case Study.

Chemistry (Weinheim an der Bergstrasse, Germany)
In the context of drug discovery, computational methods were able to accelerate the challenging process of designing and optimizing a new drug candidate. Amongst the possible atomistic simulation approaches, metadynamics (metaD) has proven very power...

Structure-induced Intelligence of Liquid Crystal Elastomers.

Chemistry (Weinheim an der Bergstrasse, Germany)
Liquid crystal elastomers (LCEs) are active soft matter-based materials with strong stimulus responsiveness and reversible, large-shape morphing capabilities. LCEs have demonstrated broad and growing applications in soft robotics, wearable devices, a...

Functional Liquid Crystal Elastomers Based on Dynamic Covalent Chemistry.

Chemistry (Weinheim an der Bergstrasse, Germany)
The marriage of liquid crystal elastomers with dynamic covalent chemistry can be a new paradigm for the development of dynamic and intelligent polymers with versatile functionalities, which is of paramount significance for many emerging applications ...

Review and Prospect: Deep Learning in Nuclear Magnetic Resonance Spectroscopy.

Chemistry (Weinheim an der Bergstrasse, Germany)
Since the concept of deep learning (DL) was formally proposed in 2006, it has had a major impact on academic research and industry. Nowadays, DL provides an unprecedented way to analyze and process data with demonstrated great results in computer vis...