AI Medical Compendium Journal:
Iranian journal of pharmaceutical research : IJPR

Showing 11 to 20 of 62 articles

Cerasome Versus Liposome: A Comparative Pharmacokinetic Analysis Following Intravenous Administration into Rats.

Iranian journal of pharmaceutical research : IJPR
BACKGROUND: Cerasomes, due to their external siloxane network, demonstrate markedly higher physicochemical stability and, therefore, easier handling and storage than liposomes.

Achieving Equitable Access to Medicines and Health Services: A COVID-19-time Recalled Matter.

Iranian journal of pharmaceutical research : IJPR
In the 21 century, while some people seek to use artificial intelligence for health services delivery, others have to surrender their health rights to meet basic needs. The gradient in health has become more pronounced in the COVID-19 crisis consider...

Phytochemicals Analysis and Some Bioactive Properties of Salisb. (EMS); Antibacterial, Antiradical and Anti-lipid Peroxidation.

Iranian journal of pharmaceutical research : IJPR
In the present study, the phenolic content by using LC MS/MS method, anticholinergic, antioxidant (metal reduction, radical and removal of lipid peroxidation), and antibacterial activities of Salisb. (EMS) extract were determined. The amount of vani...

Antimicrobial, Cytotoxic and Oxidative Stress Inhibitory Activities of Terpenoids and Flavonols from (Oliv.) P.J.H. Hurter.

Iranian journal of pharmaceutical research : IJPR
(knob thorn) is a deciduous tree distributed in savannah regions from Tanzania to South Africa used for timber but also medicinally for the treatment of convulsions, wounds, and skin problems. In this study, the biological activities of six phytocom...

Preparation and Preliminary Evaluation of Dual-functional Nanoparticles for MRI and siRNA Delivery.

Iranian journal of pharmaceutical research : IJPR
In order to improve the transfection efficiency of gene vectors and monitor the effect of gene therapy, this study prepared a drug delivery vector with dual functions. The thiourea reaction was used to synthesize polyethyleneimine (PEI, MW: 1.8 kDa) ...

Xanthatin Induces Leishmanicidal Activity by Affecting Carbon Metabolism in Amastigotes.

Iranian journal of pharmaceutical research : IJPR
Cutaneous leishmaniasis is caused by protozoa of the genus and spread by sandflies. The standard therapy for this ailment is the first-line medication of pentavalent antimonial and the second drug line of pentamidine amphotericin B. All are practice...

Protective Effects of Mill. Fruit on Carbon Tetrachloride-induced Hepatotoxicity Mediated through Mitochondria and Restoration of Cellular Energy Content.

Iranian journal of pharmaceutical research : IJPR
Quince ( Mill.) is one of the medicinal plant with a broad range of pharmacological activities such as hepatoprotective effect. The present study was conducted to evaluate the effect of aqueous extract of Mill. fruit (ACOF) against carbon tetrachlor...

Leishmanicidal, Trypanocidal and Antioxidant Activity of Amyrin-Rich Extracts from Cambess.

Iranian journal of pharmaceutical research : IJPR
AIMS: This study aimed to characterize and evaluate leishmanicidal and trypanocidal action as well as cytotoxicity on macrophages and antioxidant ability of extracts, obtained by supercritical CO and ultrasound-assisted extractions of Uvaia () leaves...

Evaluating the Effect of Dexmedetomidine on Hemodynamic Status of Patients with Septic Shock Admitted to Intensive Care Unit: A Single-Blind Randomized Controlled Trial.

Iranian journal of pharmaceutical research : IJPR
Septic shock, known as the most severe complication of sepsis, is a serious medical condition that can lead to death. Clinical symptoms of sepsis include changes in body temperature in the form of hypothermia or hyperthermia, tachypnea or hyperventil...

Anti-cholinesterase and Neuroprotective Activities of Sweet and Bitter Apricot Kernels ( L.).

Iranian journal of pharmaceutical research : IJPR
Apricot ( L.) is a fruit cultivated in various parts of the world. Both sweet and bitter kernels of apricot have been used for the treatment of different diseases such as loss of memory in Iranian traditional medicine (ITM). In the present study, the...