AI Medical Compendium Journal:
Iranian journal of pharmaceutical research : IJPR

Showing 21 to 30 of 62 articles

Mediated Synthesis of Silver Nanoparticles and Its Evaluation of Antineoplastic Activity to Combat Colorectal Cancer Cell Line.

Iranian journal of pharmaceutical research : IJPR
Several formulations of herbal plants have been extensively applied to treat diseases. ( is an Iranian traditional plant with a wide range of benefit effects on different diseases. In this study, we aimed to prepare silver nanoparticles from via th...

Quantification of 4-Methylimidazol in NMRI Mice Plasma and Cerebrospinal Fluid (CSF) by Using Liquid Chromatography Tandem Mass Spectrometry.

Iranian journal of pharmaceutical research : IJPR
A sensitive method using ion-pair extraction was developed by liquid chromatography tandem mass spectrometry (LC-MS/MS) for measurement of 4-methylimidazole (4-MI) in NMRI mice plasma and cerebrospinal fluid (CSF). Detection was done by electrospray ...

Association between Serum Vitamin D Concentration Status and Matrix Metalloproteinase-9 in Patients Undergoing Elective Percutaneous Coronary Intervention.

Iranian journal of pharmaceutical research : IJPR
Cardiovascular diseases (CVD) have become increasingly life-threatening during recent decades. Several studies have shown that matrix metalloproteinase-9 (MMP-9) plays an important role in the process of atherosclerosis and heart remodeling. On the o...

Diterpenoids from Roots of and Toxicity against Human Cancer Cell Lines.

Iranian journal of pharmaceutical research : IJPR
Further investigations on phytochemical constituents of dichloromethane extract from roots of ( led to the isolation and identification of eight known diterpenoids from this plant for the first time. The chemical structures of the purified compounds...

Evaluation of Cyclosporine Pharmacokinetic, Monitoring, and Dosing Parameters for GVHD Prophylaxis in Hematopoietic Stem Cell Transplant (HSCT) Recipients.

Iranian journal of pharmaceutical research : IJPR
Allogeneic hematopoietic stem cell transplantation (AHSCT) is a major method of treatment for different hematologic and congenital disease. Graft versus host disease (GvHD) is a life-threatening adverse effect of AHSCT. Cyclosporine is the most impor...

The Photothermal Effect of Targeted Methotrexate-Functionalized Multi-Walled Carbon Nanotubes on MCF7 Cells.

Iranian journal of pharmaceutical research : IJPR
Our goal is to reduce the release rate of methotrexate (MTX) and increase cell death efficiency.Carboxylated multi-walled carbon nanotubes (MWCNT-COOH) were functionalized with MTX as a cytotoxic agent, FA as a targeting moiety and polyethylene amine...

Effect of Amino Acid Substitutions on Biological Activity of Antimicrobial Peptide: Design, Recombinant Production, and Biological Activity.

Iranian journal of pharmaceutical research : IJPR
Recently, antimicrobial peptides have been introduced as potent antibiotics with a wide range of antimicrobial activities. They have also exhibited other biological activities, including anti-inflammatory, growth stimulating, and anti-cancer activiti...

Comparative Study of the Effects of Chamomile ( L.) and Cabergoline on Idiopathic Hyperprolactinemia: A Pilot Randomized Controlled Trial.

Iranian journal of pharmaceutical research : IJPR
Chamomile is a fascinating plant quoted in several traditional medicine texts, which has broad-spectrum pharmacological activity and medicinal uses. The aim of this study was to assess the efficacy of chamomile syrup in reducing serum prolactin in wo...

Antimicrobial Activities of Extracts and Isolated Coumarins from the Roots of Four Species Growing in Turkey.

Iranian journal of pharmaceutical research : IJPR
species have been utilized since ancient times as digestive, sedative, aphrodisiac, along with in salads or as a spice due to their special odors. The study reports isolation and characterization of bioactive compounds of , (, and ( via bioassay ...

Anticancer Activity of Polyisoprenoids from Blume. in WiDr Cells.

Iranian journal of pharmaceutical research : IJPR
Colorectal cancer is the third most common cancer world wide and has been occurred more in developing regions. The use of conventional chemotherapy agents may lead to various adverse effects. Therefore, it is required to find the potential drug for a...