Iranian journal of pharmaceutical research : IJPR
Jan 1, 2019
is a well-known genus in Leguminosae family that represented more than 800 species growing in Iran. Nevertheless, there are a few reports on plants endemic to Iran. The roots of plants are rich in saponins, flavonoids and polysaccharides that poss...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2019
The anti- activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of , , and were evaluated against epimastigotes, , , , , and dichloromethane extracts showed trypanocidal activity with i...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2019
The volatile organic compounds (VOCs) of two species ( Miller and L.) obtained by hydrodistillation (HD) and solid phase microextraction (SPME) techniques were identified by GC-FID/MS. The major compounds identified in the SPME extracts were limone...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2019
In this study, a series of novel compounds based on 5-(5-nitrothiophene-2-yl)-1,3,4-thiadiazole possessing (het) aryl thio pendant at C-2 position of thiadiazole ring is developed and evaluated as antileishmanial agents using MTT colorimetric assay. ...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2019
Therapeutic Drug Monitoring (TDM) of first-line anti-tuberculosis (TB) drugs is a decisive tool, allowing the clinician to successfully treat TB patients. The objective of the study was to develop and optimize a simple, sensitive, and reliable high-p...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2017
N-acetylcysteine (NAC) is a potent antioxidant that acts through regenerating glutathione stores and scavenging oxygen-free radicals. This study assesses the short-term effects of NAC in cadaveric kidney transplant (KT) recipients. A double blind, ra...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2017
Ischemia reperfusion injury (IRI) is one of the main causes of delayed graft function (DGF) in deceased-donor kidney transplantation (DDKT). Evidences suggest that hypertonic saline (HS) has beneficial effects on IRI. The objective of the present stu...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2017
Co-administration of norfloxacin (NFX) and tinidazole (TNZ) has been used for the treatment of gastrointestinal and urinary tract infections. Concomitant oral administration of NFX with TNZ may affect NFX absorption and consequently its blood concent...
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2017
Designing enriched probiotic supplements may have some advantages including protection of probiotic microorganism from oxidative destruction, improving enzyme activity of the gastrointestinal tract, and probably increasing half-life of micronutrient....
Iranian journal of pharmaceutical research : IJPR
Jan 1, 2017
Hexane, ethyl acetate and methanol extracts of leaves were investigated for their antibacterial activities against , , , , and . Hexane and ethyl acetate extracts were toxic to Gram-positive bacteria with inhibition zone diameters ranging between 1...